In the method using a thickening agent, the thickening agent itself remains on the surface of the tablet, so moisture does not reach the center of the tablet, and it is thought that no disintegration of the test drug was observed. This is also supported by the results of the study. On the other hand, in the water wafer method, water freely passes through the wafer and permeates into the center of the tablet, so it is thought that disintegration within the wafer may have occurred. Conventionally, a method using thickening-adjusted foods for patients with dysphagia has been adopted, but evaluating the disintegration properties of individual drugs is an important step in the medical care provided by pharmacists to patients with dysphagia. It is one of the important drug physical properties in providing information to staff and patients' families.
