Papers

Basic information

Name Kazuma Aoki
Belonging department Department of Pharmaceutical Sciences,Faculty of Pharmaceutical Sciences
Occupation name Lecturer
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Title 

The gene expression of two endoplasmic reticulum aminopeptidase 1 isoforms is regulated by distinct posttranscriptional mechanisms

					

					

						

							

								

									
Bibliography怀Type 

									
								

							

						

						
Joint Author

					

					

						

							

								

									
Summary 

									
								

							

						

						
ERAP1 is associated with various autoimmune diseases. Human ERAP1 protein has two isoforms produced by alternative splicing of the 3' terminal exon, although their functional differences have not yet been fully clarified. In this study, we showed that the isoforms undergo different posttranscriptional regulation mechanisms via their respective 3' untranslated regions.  

					

					

						

							

								

									
Magazine(name) 

									
								

							

						

						
Biochemical and Biophysical Research Communications

					

					

						

							

								

									
Date of Issue 

									
								

							

						

						
201808