Papers

Basic information

Name Kazuma Hamada
Belonging department Department of Pharmaceutical Sciences,Faculty of Pharmaceutical Sciences
Occupation name Associate Professor
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Title 

Disruption of ZO-1/claudin-4 interaction in relation to inflammatory responses in methotrexate-induced intestinal mucositis

					

					

						

							

								

									
Bibliography怀Type 

									
								

							

						

						
Joint Author

					

					

						

							

								

									
Summary 

									
								

							

						

						
This study aimed to determine how intestinal TJ proteins are altered in relation to mucosal immune responses to MTX-treatment. We found that inhibition of ZO-1 binding to claudin-4 is associated with enhanced intestinal permeability.

					

					

						

							

								

									
Magazine(name) 

									
								

							

						

						
Cancer Chemother Pharmacol. 2013, Oct;72(4):757-65

					

					

						

							

								

									
Date of Issue 

									
								

							

						

						
201310