Other Research Achievements

Basic information

Name Setsuko Nagahama
Belonging department Department of Physical Therapy,Faculty of Health and Medical Science
Occupation name Professor
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Repeated mechanical stimuli at change time intervals have influence on pressure pain threshold

Sole or Joint Author

Sole Author

Date of Issue


Conference Presentation(name)

Neuroscience 2019 (Society for Neuroscience, 49th Annual Meeting) , October, 2019, Chicago, USA


Nociceptors in the skin are present in free nerve endings of Aδ-fibers and C-fibers. The Aδ-fibers develop picking and fast pain in response to mechanical stimulation. It is well known that pain receptor is non-adapting type. There is little report about pain sensory and adaptation mechanism of Aδ- fibers, and it is not clear of pain sensory mechanism of Aδ- fibers.
The author reported that repeated mechanical stimuli to nociceptor increase pressure pain thresholds, PPTs (Neuroscience 2018). A total of 16 participants took part in the study (ranging from 20 to 22 years; 8 males and 8 females). In 7, 10, 20, 30-seconds intervals the PPTs were significantly increased. In contrast, there were increase tendency of the PPTs in 5-seconds intervals, but there were no significant changes of them. This study focused on the adaptation of pain sensory by measuring the influence of repeated mechanical pain stimuli at 5-seconds intervals on PPTs.