Primary polydipsia, but not accumulated ceramide, causes lethal renal damage in saposin D-deficient mice.

Hisaki H, Matsuda J, Tadano-Aritomi K, Uchida S, Okinaga H, Miyagawa M, Tamamori-Adachi M, Iizuka M, Okazaki T.

Am J Physiol Renal Physiol. 2012 Oct;303(7):F1049-59. doi: 10.1152/ajprenal.00047.2012. Epub 2012 Jul 25.