Heat Shock Protein (HSP) that increases by the hyperthermia stimulation is assumed for the possibility of promoting the reproduction and hypertrophy of skeletal muscles. The influence that the ultrasound therapy gives to a diachronic change of the HSP appearance is not examined. The purpose of this study was to investigate the influence that the ultrasound stimulation gives to the diachronic change of rat skeletal muscle HSP appearance. Male Sprague-Dawley rats were divided into two groups (n=17/group) :
US20(1W/cm2,1MHz,15min20%puls)andUS100(1W/cm2,1MHz,15min,100%pu ls).
The soleus and plantaris muscle were dissected immediately after ultrasound stimulate and at 24 and 48h. The amount of the HSP72 (227±132%) appearance significantly increased in the plantaris muscle after 24 hours of US100 compared with Con, while there was no significant increase in the soleus muscle. There is a possibility that the significant increase in the amount of the HSP appearance is brought by the muscle temperature rise.