Papers

Basic information

Name Dai Nakae
Belonging department Animal Medical Course,Department of Medical Sports,Faculty of Health Care and Medical Sports
Occupation name Professor
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Title 

Effects of Siraitia grosvenorii extract on NASH-like lesions in SD rats fed a choline-deficient, methionine-lowered, L-amino acid-defined diet.

					

					

						

							

								

									
Bibliography　Type 

									
								

							

						

						
Joint Author

					

					

						

							

								

									
Summary 

									
								

							

						

						

 Siraitia grosvenorii is extract (SGE) inhibited histopathological changes, NF-κB activation and CD44 expression in the rat model of non-alcoholic steatohelatitis (NASH). SGE administration inhibited these lesions, similar to CD44, a factor that controls hepatic inflammation and fibrosis.  SGE was found to be useful for preventing and treating NASH.

					

					

						

							

								

									
Magazine(name) 

									
								

							

						

						
Japanese Journal of Toxicologic Pathology

					

					

						

							

								

									
Date of Issue 

									
								

							

						

						
202301