Papers

Basic information

Name Yoshihito Nakatani
Belonging department Department of Pharmaceutical Sciences,Faculty of Pharmaceutical Sciences
Occupation name Professor
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Title 

Cytosolic prostaglandin E synthase is involved in c-Fos expression in rat fibroblastic 3Y1 cells

					

					

						

							

								

									
Bibliography怀Type 

									
								

							

						

						
Joint Author

					

					

						

							

								

									
Summary 

									
								

							

						

						
Here we report the involvement of cPGES/p23 in c-Fos expression. A stable knockdown of cPGES/p23 in cultured fibroblasts not only reduced serum-induced c-Fos expression, but also decreased the phosphorylation of extracellular signal regulated kinase (ERK). These results suggest that cPGES/p23 is involved in the activation of ERK to promote c-Fos expression.

					

					

						

							

								

									
Magazine(name) 

									
								

							

						

						
Biol. Pharm. Bull.

					

					

						

							

								

									
Date of Issue 

									
								

							

						

						
201711