Papers

Basic information

Name Yoichi Ezura
Belonging department Department of Occupational Therapy,Faculty of Health and Medical Science
Occupation name Professor
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Title 

Profilin-1 negatively controls osteoclast migration by suppressing the protrusive structures based on branched actin filaments.


					

					

						

							

								

									
Bibliography怀Type 

									
								

							

						

						
Joint Author

					

					

						

							

								

									
Summary 

									
								

							

						

						
To understand cellular base of postnatal osteolysis in osteoclast specific Pfn1-KO mice, increased index of protrusive structures of cell boundaries was correlated with their migration. Significant suppression of osteoclast migration observed more extensively in Pfn1-cKO than in control indicated causative involvement of increased branched actin filament formation.

					

					

						

							

								

									
Magazine(name) 

									
								

							

						

						
J Bone Miner Metab.

					

					

						

							

								

									
Date of Issue 

									
								

							

						

						
202204