Papers

Basic information

Name Shoichi Komine
Belonging department Department of Acupuncture and Moxibustion,Faculty of Health Care
Occupation name Assistant Professor
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Title 

Cytoprotective Role of Nrf2 in Electrical Pulse Stimulated C2C12 Myotube.

					

					

						

							

								

									
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Joint Author

					

					

						

							

								

									
Summary 

									
								

							

						

						
Analysis using differentiated myoblasts and a cellular electrical contraction apparatus showed that excessive contraction of myoblasts caused excessive ROS production in mitochondria. The transcription factor Nrf2, a master regulator of antioxidant enzymes, and its downstream genes worked to scavenge the generated ROS.

					

					

						

							

								

									
Magazine(name) 

									
								

							

						

						
PLoS One. 2015;10(12):e0144835

					

					

						

							

								

									
Date of Issue 

									
								

							

						

						
201511