Papers

Basic information

Name Ken'ichi Kurihara
Belonging department Department of Pharmaceutical Sciences,Faculty of Pharmaceutical Sciences
Occupation name Professor
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Title 

Discovery of progesterone receptor agonists and antagonists inspired by the fungal metabolite PF1092C.

					

					

						

							

								

									
Bibliography怀Type 

									
								

							

						

						
Joint Author

					

					

						

							

								

									
Summary 

									
								

							

						

						
In the course of our microbial screening studies to find novel nonsteroidal PR ligands, the fungal metabolites PF 1092 A, B and C were isolated from extracts of cell cultures of the rare fungus Penicillium oblatum PF 1092. In this report, we mainly describe the synthesis and SAR of these derivatives, as new nonsteroidal PR ligands.

					

					

						

							

								

									
Magazine(name) 

									
								

							

						

						
J. Synth. Org. Chem. Jpn.

					

					

						

							

								

									
Date of Issue 

									
								

							

						

						
200605