Papers

Basic information

Name Takashi Izumi
Belonging department Department of Acupuncture and Moxibustion,Faculty of Health Care
Occupation name Professor
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Title

CD8+ regulatory T cells are critical in prevention of autoimmune-mediated diabetes (査読付)

Bibliography Type

Joint Author

Summary

Using mice, we found that infection with intestinal parasitic nematodes suppressed the onset of type 1 diabetes. The mechanism is that the parasite secretes a sugar called trehalose, which causes the growth of Ruminococcus intestinal bacteria, which induces CD8Treg, which stops the destruction of pancreatic cells and causes the onset of type 1 diabetes. Was revealed to be suppressed.

Magazine(name)

Nature Communications

Date of Issue

202004