Papers

Basic information

Name Takashi Izumi
Belonging department Department of Acupuncture and Moxibustion,Faculty of Health Care
Occupation name Professor
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Title 

Identification of 9-hydroxyoctadecadienoic acid and other oxidized free fatty acids as ligands of the G protein-coupled receptor G2A

					

					

						

							

								

									
Bibliography怀Type 

									
								

							

						

						
Joint Author

					

					

						

							

								

									
Summary 

									
								

							

						

						
G2A is a G protein-coupled receptor that is predominantly expressed in lymphoid tissues and macrophages. It causes cell cycle arrest and is induced by DNA damage stimulation and oxidative stress. We reported that G2A functions as a receptor for 9-HODE and other oxidized free fatty acids. G2A may have a biological role in a variety of pathological conditions, including atherosclerosis.

					

					

						

							

								

									
Magazine(name) 

									
								

							

						

						
Journal of Biological Chemistry

					

					

						

							

								

									
Date of Issue 

									
								

							

						

						
200512