Papers

Basic information

Name Yoshimi Shimizu
Belonging department Department of Pharmaceutical Sciences,Faculty of Pharmaceutical Sciences
Occupation name Lecturer
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Title 

The function of SARS-CoV-2 spike protein is impaired by disulfide-bond disruption with mutation at cysteine-488 and by thiol-reactive N-acetyl-cysteine and glutathione

					

					

						

							

								

									
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Joint Author

					

					

						

							

								

									
Summary 

									
								

							

						

						
 We showed that the substitution of Cys-488 with alanine impaired pseudotyped SARS-CoV-2 infection, syncytium formation, and cell-cell fusion triggered by SARS-CoV-2 spike expression. 

					

					

						

							

								

									
Magazine(name) 

									
								

							

						

						
 Biochemical and Biophysical Research Communications 

					

					

						

							

								

									
Date of Issue 

									
								

							

						

						
202201