JM-1232(-) (JM) is a novel isoindoline derivative with sedative and hypnotic activities that are mediated by binding to the benzodiazepine site of the Gamma-aminobutyric acid type A (GABAA) receptor.
We analyzed the neuroprotective effects of JM-1232 (-) using rat hippocampal slice cultures exposed to oxygen-glucose deprivation (OGD).