Papers

Basic information

Name Hiroko Hashida
Belonging department Department of Health and Dietetics,Faculty of Health and Medical Science
Occupation name Lecturer
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Title 

High dose of commercial products of kava (Piper methysticum) markedly enhanced hepatic cytochrome P450 1A1 mRNA expression with liver enlargement in rats

					

					

						

							

								

									
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Joint Author

					

					

						

							

								

									
Summary 

									
								

							

						

						
Commercial products (herbal supplements) containing the kava plant (Piper methysticum), known to have the anxiolytic activity are the suspicion of a potential liver toxicity. We have investigated the effects of administration of commercial kava products on gene expression of hepatic CYP1A isoforms in rats.

					

					

						

							

								

									
Magazine(name) 

									
								

							

						

						
Food and Chemical Toxicology

					

					

						

							

								

									
Date of Issue 

									
								

							

						

						
200812