Papers

Basic information

Name Ryohei Yanoshita
Belonging department Department of Pharmaceutical Sciences,Faculty of Pharmaceutical Sciences
Occupation name Professor
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Title 

Stability of human salivary extracellular vesicles containing dipeptidyl peptidase IV under simulated gastrointestinal tract conditions

					

					

						

							

								

									
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Joint Author

					

					

						

							

								

									
Summary 

									
								

							

						

						
The EVs from human whole saliva remained  partially lost their membrane integrity in the presence of pancreatin and sodium cholate, indicating that they may be destabilized after passing through the duodenum. Although several associated proteins, such as mucin 5B and CD9 were degraded, DPP IV was stable, and its activity was retained under the simulated gastrointestinal conditions.

					

					

						

							

								

									
Magazine(name) 

									
								

							

						

						
Biochem Biophys Rep. 27:101034

					

					

						

							

								

									
Date of Issue 

									
								

							

						

						
202106