Department of Pharmaceutical Sciences,Faculty of Pharmaceutical Sciences
Occupation name
Associate Professor
researchmap researcher code
researchmap agency
Title
Tumor-targeted delivery of novel trivalent anti-TRAIL-R1 VHHs by Bifidobacterium longum.
Sole or Joint Author
Joint Author
Date of Issue
201603
Conference Presentation(name)
The 136th Annual Meeting of the Pharmaceutical Society of Japan (Yokohama)
Summary
We showed that intravenous administration of anaerobic Bifidobacteria secreting novel trivalent VHHs targeting death receptor 4 (TRAIL-R1) suppressed the tumor growth in tumor-bearing mice.