Biocompatibility of Hemodiafilters

During hemodiafiltration (HDF), hemodiafilter-blood contact leads to both direct and indirect activation of platelets and leukocytes via complement activation, resulting in reactions like platelet aggregation and increased vascular permeability. While solute removal and ultrafiltration are primary selection criteria for hemodiafilters, biocompatibility is also crucial for safe HDF treatment.

Biomedical Engineering Therapy